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Especially when accompanied by shortness of breath, these symptoms can indicate cardiac amyloidosis, Zoghbi says. “It’s a problem of protein misfolding,” he explains. “The protein, which ...
Tadalafil is an annulated 2,5-diketopiperazine. [25] It is also a 1,2,3,4-tetrahydro-β-carboline. Tadalafil can be synthesized starting from (D)-tryptophan methyl ester and piperonal via a Pictet–Spengler reaction. This is followed by condensations with chloroacetyl chloride and methylamine to complete the diketopiperazine ring: [26]
[25]: 130 According to Li Chuan, a senior executive at Alibaba, the company was planning in 2013 to open traditional brick and mortar retail outlets in partnership with Wanda Group, a Chinese real estate company. [26] Additionally, Alibaba purchased a 25% stake in Hong Kong-listed Chinese department store chain Intime Retail in early 2014. [27]
Mathematical description. The raised-cosine filter is an implementation of a low-pass Nyquist filter, i.e., one that has the property of vestigial symmetry. This means that its spectrum exhibits odd symmetry about , where is the symbol-period of the communications system. Its frequency-domain description is a piecewise -defined function, given ...
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